1,4-Bis[3,4-dihydro-2(1H)-quinolinon-7-oxy]butane
2(1H)-Quinolinone,7,7'-[1,4-butanediylbis(oxy)]bis[3,4-dihydro-
CAS: 882880-12-8
Molecular Formula: C22H24N2O4
1,4-Bis[3,4-dihydro-2(1H)-quinolinon-7-oxy]butane - Names and Identifiers
| Name | 2(1H)-Quinolinone,7,7'-[1,4-butanediylbis(oxy)]bis[3,4-dihydro- |
| Synonyms | Aripiprazole IMpurity D Aripiprazole USP impurty D Aripiprazole USP impurity D Aripiprazole Diquinoline Butanediol Impurity 1,4-Bis[3,4-dihydro-2(1H)-quinolinon-7-oxy]butane 7,7'-[1,4-Butanediylbis(oxy)]bis[3,4-dihydro-2(1H)-quinolinone 2(1H)-Quinolinone,7,7'-[1,4-butanediylbis(oxy)]bis[3,4-dihydro- 7,7'-(butane-1,4-diylbis(oxy))bis(3,4-dihydroquinolin-2(1H)-one) |
| CAS | 882880-12-8 |
1,4-Bis[3,4-dihydro-2(1H)-quinolinon-7-oxy]butane - Physico-chemical Properties
| Molecular Formula | C22H24N2O4 |
| Molar Mass | 380.44 |
| Density | 1.226±0.06 g/cm3(Predicted) |
| Melting Point | 215 - 217°C |
| Boling Point | 673.2±55.0 °C(Predicted) |
| Solubility | DMSO (Slightly), Ethyl Acetate (Slightly, Heated), Methanol (Sparingly) |
| Appearance | Solid |
| Color | White to Off-White |
| pKa | 14.11±0.20(Predicted) |
| Storage Condition | Refrigerator |
1,4-Bis[3,4-dihydro-2(1H)-quinolinon-7-oxy]butane - Introduction
2(1H)-Quinolinone,7,7 '-[1,4-butanediylbis(oxy)]bis[3,4-dihydro-(2(1H)-Quinolinone,7,7'-[1, 4-butylbis (oxy)]bis[3,4-dihydro-)) is an organic compound. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: 2(1H)-Quinolinone,7,7 '-[1,4-butylylbis (oxy)]bis[3,4-dihydro-is solid, in the form of white crystals or crystalline powder at room temperature.
-Solubility: It is soluble in alcohol and Ketone solvents, insoluble in water.
-Melting point: 2(1H)-Quinolinone,7,7 '-[1,4-butylylbis (oxy)]bis[3,4-dihydro-The melting point range is usually between 70-90 degrees Celsius.
Use:
2(1H)-Quinolinone,7,7 '-[1,4-butylbis (oxy)]bis[3,4-dihydro-commonly used as pharmaceutical intermediates. It plays an important role in the pharmaceutical industry and is often used in the synthesis of biologically active aripiprazole drugs.
Preparation Method:
The Main synthesis method is to synthesize 2(1H)-Quinolinone,7,7 '-[1,4-butylbis (oxy)]bis[3,4-dihydro-. The specific synthesis route can be optimized according to different requirements, and the common synthesis methods include catalytic reduction, cyclization reaction and condensation reaction.
Safety Information:
- 2(1H)-Quinolinone,7,7 '-[1,4-butylbis (oxy)]bis[3,4-dihydro-may cause potential harm to human health, therefore, it is necessary to take appropriate protective measures when handling and using.
- 2(1H)-Quinolinone,7,7 '-[1,4-butylylbis (oxy)]bis[3,4-dihydro-keep away from fire and high temperature environment, avoid direct exposure to light.
-When using or handling 2(1H)-Quinolinone,7,7 '-[1,4-butylbis (oxy)]bis[3,4-dihydro, wear appropriate personal protective equipment such as chemical protective gloves, safety glasses and protective clothing.
-If 2(1H)-Quinolinone,7,7 '-[1,4-butylbis (oxy)]bis[3,4-dihydro-, flush immediately with plenty of water and seek medical help.
Note: The above information is for reference only. The specific use and handling should follow the safety technical instructions and operating procedures provided by the manufacturer.
Nature:
-Appearance: 2(1H)-Quinolinone,7,7 '-[1,4-butylylbis (oxy)]bis[3,4-dihydro-is solid, in the form of white crystals or crystalline powder at room temperature.
-Solubility: It is soluble in alcohol and Ketone solvents, insoluble in water.
-Melting point: 2(1H)-Quinolinone,7,7 '-[1,4-butylylbis (oxy)]bis[3,4-dihydro-The melting point range is usually between 70-90 degrees Celsius.
Use:
2(1H)-Quinolinone,7,7 '-[1,4-butylbis (oxy)]bis[3,4-dihydro-commonly used as pharmaceutical intermediates. It plays an important role in the pharmaceutical industry and is often used in the synthesis of biologically active aripiprazole drugs.
Preparation Method:
The Main synthesis method is to synthesize 2(1H)-Quinolinone,7,7 '-[1,4-butylbis (oxy)]bis[3,4-dihydro-. The specific synthesis route can be optimized according to different requirements, and the common synthesis methods include catalytic reduction, cyclization reaction and condensation reaction.
Safety Information:
- 2(1H)-Quinolinone,7,7 '-[1,4-butylbis (oxy)]bis[3,4-dihydro-may cause potential harm to human health, therefore, it is necessary to take appropriate protective measures when handling and using.
- 2(1H)-Quinolinone,7,7 '-[1,4-butylylbis (oxy)]bis[3,4-dihydro-keep away from fire and high temperature environment, avoid direct exposure to light.
-When using or handling 2(1H)-Quinolinone,7,7 '-[1,4-butylbis (oxy)]bis[3,4-dihydro, wear appropriate personal protective equipment such as chemical protective gloves, safety glasses and protective clothing.
-If 2(1H)-Quinolinone,7,7 '-[1,4-butylbis (oxy)]bis[3,4-dihydro-, flush immediately with plenty of water and seek medical help.
Note: The above information is for reference only. The specific use and handling should follow the safety technical instructions and operating procedures provided by the manufacturer.
Last Update：2024-04-09 20:49:11
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CAS: 882880-12-8
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